
Constantine Dimitrakakis was born in Rethymno and graduated from the Medical School of the University of Athens.
He specialized in Obstetrics Gynecology at the 1st University Obstetrics Gynecology Clinic, Alexandra Hospital and holds a PhD from the University of Athens with a dissertation on breast cancer.
He trained in the United States at the National Institutes of Health (NIH) in Womens ’Health at the National Institute of Child Health and Human Development.
He also attended the Department of Obstetrics Gynecology and the Lombardi Cancer Center at Georgetown University Hospital, Washington DC.

He has worked at the IASO Breast Center in Athens for two years and today he collaborates with REA.
He is an Associate Professor at the Medical School of the University of Athens at the 1st Obstetrics Gynecology Clinic at Alexandra Hospital, supports the Obstetrics & Gynecology work of the Clinic and is the Head of the Breast Department which is certified by the European Breastfeeding Organizations (EUSOMA, UEMS, ESSO) and is a member of the Breast Centers Network.
From this position he organizes and regulates the operation of the Breast Center, supervises the Clinic for the monitoring of women at High Risk for Breast Cancer, organizes Conferences and Seminars and participates in research collaborations with other centers in Greece and abroad. He trains students in breast surgery, specialists and specialized doctors, fellows, research associates and PhD candidates.
He specializes in further postgraduate activities in gene testing, Breast imaging, Oncoplasty and techniques related to the modern treatment of breast cancer.
He is internationally known mainly for his thorough research on the effects of hormone therapies on the breast.
He has published numerous articles in international journals, has thousands of citations (citations) in the literature, has received awards for his research work and participates in international conferences as a guest speakergiving lectures.
Finally he has written medical books, in Greek and foreign languages.
He is a member of many scientific societies and since 2015 he is the president of the Hellenic Gynecological Society of Breast Diseases (EGEPAM).

∘ Aπονομή του Βραβείου «Γ. Παπανικολάου» της P&G Ελλάς για την περίοδο 2020-22, ύψους 20.000€ για την περίοδο 2020-2022 στην εργασία με τίτλο: «Ο ρόλος των αντιπρογεστερινοειδών στην έκφραση της Γκαλεκτίνης – 3 και στη θεραπεία του καρκίνου του μαστού σε ενα ζωΐκό πειραματικό μοντέλο», Αθήνα 2020
∘ Fellow of the European Board of Surgery (F.E.B.S.)-Breast Surgery, Honorary Diploma. European Board of Surgery of the UEMS and the Division of Breast Surgery, June 2018
∘ 1ο βραβείο “Ελληνικής και Διεθνούς Εταιρείας Μοριακά Στοχευμένων και Εξατομικευμένων Θεραπειών” για την εργασία με τίτλο: “Evaluation of Met-polymorphisms in patient with triple negative breast cancer” Μάιος 2017
∘ 2ο βραβείο “Ελληνικής και Διεθνούς Εταιρείας Μοριακά Στοχευμένων και Εξατομικευμένων Θεραπειών” για την εργασία με τίτλο: «προοπτική μελέτη εκτίμησης της σημασίας του Oncotype Dx στη λήψη απόφασης για χορήγηση χημειοθεραπείας σε ασθενείς με Ca μαστού». Μάιος 2016
∘ Abstract Awarded Travel Grant, IMPAKT Breast Cancer Conference, Brussels, Belgium, 6-8 May 2010. “Analysis and prognosis of triple negative basal like breast cancer”
∘ Abstract Awarded Travel Grant, IMPAKT Breast Cancer Conference, Brussels, Belgium, 6-9 May 2009. “99m Tc-(V)DMSA uptake and mammographic breast density – relationship with Calcitonin Gene Related Peptide (CGRP) expression in pure invasive ductal (IDC) and mixed invasive with extensive in situ ductal carcinomas (IDC+DCIS)”
∘ Βραβείο καλύτερης Αναρτημένης Ανακοίνωσης στο 11ο Πανελλήνιο Συνέδριο Μαστολογίας. Αθήνα, 2-4 Απριλίου 2009. «Μαστογραφική πυκνότητα και σπινθηρογράφημα μαστού με 99m tc-(v)dmsa – συσχέτιση με την έκφραση του calcitonin gene related peptide (cgrp) στο πορογενές διηθητικό (idc) και διηθητικό με εκτεταμένο in situ πορογενές καρκίνωμα του μαστού (idc+dcis)»
∘ Υποτροφία από Επιτροπή Ερευνών του Πανεπιστημίου Αθηνών για το ερευνητικό πρόγραμμα με τίτλο «Μελέτη των παραγόντων κινδύνου για καρκίνο μαστού στην Ελλάδα». Χορηγία 6500 ευρώ. Κωδικός προγράμματος 70/4/9007, Αθήνα Απρίλιος 2007.
∘ “Women in Endocrinology” Award, The Endocrine Society’s 85th annual meeting, Philadelphia, June 19-22, 2003
∘ “Scholar-in-Training Award” στο 2002 ετήσιο συνέδριο της «Αμερικανικής Εταιρείας για την Έρευνα στον καρκίνο» (American Association for Cancer Research”. San Francisco, April 2002.
∘ 2002 FARE award (Fellows Award for Research Excellence) at the National Institutes of Health, USA
∘ “The Endocrine Society” Travel Grant Award for exceptional research presented at the 83rd annual meeting of the Endocrine Society, Denver, Colorado, June 20-23, 2001.
∘ “Οδυσσέας Καλλιγιάννης” για την καλύτερη μελέτη στο Παγκρήτιο Ιατρικό Συνέδριο, Νοέμβριος 2000.
∘ “Aλιβιζάτος” για την καλύτερη μελέτη ορθοκολικού καρκίνου από την Ελληνική Εταιρεία Γενικής Χειρουργικής, 1996.
∘ Δόκιμο μέλος της “Ελληνικής Εταιρείας Ενδοσκοπικής Χειρουργικής και άλλων Επεμβατικών Τεχνικών” για την επίδοση του στην ενδοσκοπική χειρουργική. Αθήνα, Δεκέμβριος 1995.
∘ Βραβεία προόδου και Αριστεία προόδου από το ΥΠΕΠΘ για τις 3 τάξεις του Λυκείου κατά τα έτη 1981-83.
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Androgens and the breast - Constantine Dimitrakakis and Carolyn Bondy
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Low salivary testosterone levels in patients with breast cancer - Constantine Dimitrakakis, David Zava, Spyros Marinopoulos, Alexandra Tsigginou, Aris Antsaklis, Rebecca Glaser
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Incidence of invasive breast cancer in women treated with testosterone implants: a prospective 10-year cohort study - Rebecca L. Glaser, Anne E. York and Constantine Dimitrakakis
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Adding the power of iodinated contrast media to the credibility of mammography in breast cancer diagnosis - Alexandra Tsigginou, Christina Gkali, Athanasios Chalazonitis, Eleni Feida, Dimitrios Efthymios Vlachos, Flora Zagouri, Ioannis Rellias, Constantine Dimitrakakis
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Discrepancies of current recommendations in breast cancer follow-up: a systematic review - Anastasios Kyriazoglou, Flora Zagouri, Despina Fotiou, Constantinos Dimitrakakis, Spyros Marinopoulos, Roubini Zakopoulou, Maria Kaparelou, Anna Zygogianni, Meletios Athanasios Dimopoulos
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Does Pregnancy-Associated Breast Cancer Imply a Worse Prognosis? A Matched Case-Case Study - Constantine Dimitrakakis, Flora Zagouri, Alexandra Tsigginou, Spyros Marinopoulos, Theodoros N. Sergentanis, Antonis Keramopoulos, George C. Zografos, Konstantina Ampela, Dimosthenis Mpaltasa,Christos Papadimitriou, Meletios-Athanassios Dimopoulos, Aris Antsaklis
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Androgens and Breast Cancer in Men and Women- Constantine Dimitrakakis
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Cancer in pregnancy: disentangling treatment modalities - Flora Zagouri, Constantine Dimitrakakis, Spyridon Marinopoulos, Alexandra Tsigginou, Meletios-Athanassios Dimopoulos
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Androgens and mammary growth and neoplasia - Constantine Dimitrakakis, Jian Zhou, and Carolyn A. Bondy
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The possible role of p53 and bcl-2 expression in cervical carcinomas and their premalignant lesions - C Dimitrakakis, G Kymionis, E Diakomanolis, I Papaspyrou, A Rodolakis, I Arzimanoglou, E Leandros, S Michalas
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Prevalence of BRCA1 and BRCA2 mutations in unselected breast cancer patients from Greece - Chrissovaladis Koumpis, Constantine Dimitrakakis, Aris Antsaklis, Robert Royer, Shiyu Zhang, Steven A Narod and Joanne Kotsopoulos
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Cumulative BRCA mutation analysis in the Greek population confirms that homogenous ethnic background facilitates genetic testing - Alexandra Tsigginou1, Fotios Vlachopoulos, Iordanis Arzimanoglou, Flora Zagouri and Constantine Dimitrakakis
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Testosterone therapy in women: Myths and misconceptions - Rebecca Glaser, Constantine Dimitrakakis
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Breast cancer treatment in women over the age of 80: A tailored approach - Rebecca Glaser, Spyridon Marinopoulos, Constantine Dimitrakakis
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Testosterone and breast cancer prevention - R Glaser, C Dimitrakakis
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A physiologic role for testosterone in limiting estrogenic stimulation of the breast - Constantine Dimitrakakis, Jian Zhou, Jie Wang, Alain Belanger, Fernand LaBrie, Clara Cheng, Douglas Powell, Carolyn Bondy
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Breast cancer incidence in postmenopausal women using testosterone in addition to usual hormone therapy - Constantine Dimitrakakis, Robert A Jones, Aiyi Liu, Carolyn A Bondy
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Rapid response of breast cancer to neoadjuvant intramammary testosterone-anastrozole therapy: neoadjuvant hormone therapy in breast cancer - Rebecca L Glaser, Constantine Dimitrakakis
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Subcutaneous testosterone-letrozole therapy before and concurrent with neoadjuvant breast chemotherapy: clinical response and therapeutic implications - Rebecca L Glaser, Anne E York, Constantine Dimitrakakis
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Breast Cancer in Women Aged 25 Years and Younger - Constantine Dimitrakakis, Alexandra Tsigginou, Flora Zagouri, Spyros Marinopoulos, Theodoros N. Sergentanis, Antonis Keramopoulos, Paraskevi Liakou, George C. Zografos, Christos A. Papadimitriou, Meletios-Athanassios Dimopoulos, and Aris Antsaklis
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Expression of ARs in triple negative breast cancer tumors: a potential prognostic factor? - Aris Giannos, Martin Filipits, Flora Zagouri, Anita Brandstetter, Alexandra Tsigginou, Maria Sotiropoulou, Irene Papaspyrou, Theodoros N Sergentanis, Theodora Psaltopoulou, Alexandros Rodolakis, Aris Antsaklis, Meletios-Athanasios Dimopoulos, Constantine Dimitrakakis
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Breast elastography: How we do it - Christina A Gkali, Athanasios N Chalazonitis, Eleni Feida, Maria Sotiropoulou, Aris Giannos, Alexandra Tsigginou, Constantine Dimitrakakis
REVIEWER ΣΕ ΠΕΡΙΟΔΙΚΑ
Reviewer σε αρκετά επιστημονικά περιοδικά όπως: The Breast, Cancer Letters, Journal of Clinical Endocrinology and Metabolism, Breast Cancer Research, European Journal of Cancer Care, Future Medicine, Womens Health, BMC Research Notes, BioMed Research International, Spandidos Publications και άλλα περιοδικά του BioMed Central.
ΣΥΓΓΡΑΦΗ ΒΙΒΛΙΩΝ
Κων/νος Δημητρακάκης «Ογκοπλαστική μαστού», υπό συγγραφή
Κων/νος Δημητρακάκης, Αντώνιος Κεραμόπουλος “Καρκίνος μαστού και μοριακή βιολογία” - Επιστημονικές Εκδόσεις "Γρ. Παρισιάνος", Αθήνα, 2000.
ΣΥΓΓΡΑΦΗ ΚΕΦΑΛΑΙΩΝ ΣΕ ΒΙΒΛΙΑ
Constantine Dimitrakakis “Breast Elastography:Basic Principles and Interpretation of Clinical Cases”, 2018, Jaypee Brothers Medical Publishers
«Καρκίνος Μαστού» κεφάλαιο σε σύγγραμμα: «Μαιευτική και Γυναικολογία» 2018, Broken Hill Publishers LTD
Constantine Dimitrakakis: “Breast Ca in pregnancy (pathology, staging, imaging, surgery, radiotherapy, chemoTx, hormonal Tx)”. HESMO Guidelines taskforce
Constantine Dimitrakakis «Androgens and breast cancer in men and women» in Endocrinology and Metabolism Clinics of North America στο κεφάλαιο Hormones and Cancer 2011 Sep;40(3):533-47
Κεφάλαιο 83, Μαστός (σ 855-894) στο σύγγραμμα: «Μαιευτική και Γυναικολογία» Αριστείδη Αντσακλή, Εκδόσεις Παρισιάνου, 2008.
Constantine Dimitrakakis and Carolyn Bondy. “The role of androgens in mammary gland growth and neoplasia” in the book: “Recent Research Developments in Endocrinology”, Transworld Research Network, Endocrinology vol.3, 2002
Carolyn Bondy and Constantine Dimitrakakis. “Androgens and breast cancer risk” in the book: “Menopause, the state of the art” Parthenon Editions, New York, 2002.
CA Bondy, C Dimitrakakis “Androgens in the Climacteric” Menopause: The State of the Art-Research and Practice, 2002 (pages 28), Taylor & Francis
ΜΕΤΑΦΡΑΣΕΙΣ
Έγχρωμη Διάγνωση Μαιευτική και Γυναικολογία. Symonds * Macpherson.- Μετάφραση: Κων/νος Δημητρακάκης - Επιστημονικές Εκδόσεις "Γρ. Παρισιάνος", Αθήνα, 1997.